 genome annotation, how to map genic regions to a genome |
Archived topics can be found at Bioinformatics and Biostatistics.
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 Jun 4 2009, 12:07 AM
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Enthusiast  Group: Active Members Posts: 20 Joined: 31-January 09 Member No.: 6846  |
HI!
I have genomic sequences of a human chromosome, and like to annotate it. Since there might be structural variants I can't simply use the positions provided e.g. by ensemble databases. I thought doing a BLAST-search, but I'm not sure if this is the right way, since the genomic DNA contains the introns. How are those things usually done on a large scale? Should I only use the exons as a query? Thanks for your help. |
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Jun 26 2009, 09:36 AM
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#2
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 Control Panel Group: Active Members Posts: 152 Joined: 5-February 09 From: In Many Hearts - Soon Coming to Yours Member No.: 7000 |
QUOTE (dersven @ Jun 4 2009, 01:07 AM)  HI! I have genomic sequences of a human chromosome, and like to annotate it. Since there might be structural variants I can't simply use the positions provided e.g. by ensemble databases. I thought doing a BLAST-search, but I'm not sure if this is the right way, since the genomic DNA contains the introns. How are those things usually done on a large scale? Should I only use the exons as a query? Thanks for your help. You may want to check out some genome annotation tools or powerpoints search results to see how this is done. |
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