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> why do macrophages detach with lidocaine ?, mechanism of detachment
celbio
post Jul 12 2002, 12:58 AM
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Dear fellow researchers

We are currently using lidocaine to detach our macrophages from the petri dish.
But we havn't got a clue about the mechanisms of detachment and whether it has any other effects irreversible on the function of our macrophages.

does anybody know the answer to our question ?

Greeting Edwin And Ester

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alloyd
post Jul 16 2002, 10:33 AM
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The lidocaine changes the shape of the macrophages to a more spherical conformation rather than the amoeba-like state they assume on the dish
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