All-new geek quotes, modified to celebrate the new forum - (Jan/26/2009 )
Mike Nelson: Well, again we're doomed.
Mystery Science Theater 3000
or should I use:
Quark: All I know is that any marriage where the female is allowed to speak and wear clothing is doomed to failure.
Star Trek: Deep Space Nine
Cindy Vortex: Is this one of those macho things?
Jimmy Neutron: Boy Genius
but this one's better......
Natalie: That's paranoid rubbish!
Life Is Sweet
Richard Hammond: The internet. 95% of it is rubbish.
Brainiac: Science Abuse
Mickey Smith: Yeah! Who told you that? He did. That's exactly what an internet lunatic murderer would say.
Doctor Who
Stephen Colbert: Sometimes it takes a crazy person to see the truth. If so, I'm a freaking lunatic.
The Colbert Report
Capt. John Sheridan: You know, it's funny, I was thinking about what you said, that the preeminent truth of our age is that you cannot fight the system. But if, as you say, the truth is fluid, that the truth is subjective, then maybe you can fight the system. As long as just one person refuses to be broken, refuses to bow down.
Babylon 5
Dr. House: Nonconformity - right. I can't remember the last time saw a twenty-something kid with a tattoo of an Asian letter on his wrist. You are one wicked free thinker! You want to be a rebel? Stop being cool. Wear a pocket protector like he does, and get a hair cut like the Asian kids that don't leave the library for twenty hour stretches. They're the ones who don't care what you think.
House M.D. 
Morpheus: The Matrix is a system, Neo. That system is our enemy. But when you're inside, you look around, what do you see? Businessmen, teachers, lawyers, carpenters. The very minds of the people we are trying to save. But until we do, these people are still a part of that system and that makes them our enemy. You have to understand, most of these people are not ready to be unplugged. And many of them are so inured, so hopelessly dependent on the system, that they will fight to protect it.
The Matrix
Miss Lemon: It's nearly complete, you see. My system.
Agatha Christie: Poirot
Annorax: Congratulations. You almost wiped out 8000 civilizations.
Star Trek: Voyager