(Department of Pathology, UT Southwestern Medical Center)
CLASSIFI (Cluster Assignment for Biological Inference) is a data-mining tool that can be used to identify significant co-clustering of genes with similar functional properties (e.g. cellular response to DNA damage). Briefly, CLASSIFI uses the Gene OntologyTM (GO) gene annotation scheme to define the functional properties of all genes/probes in a microarray data set, and then applies a cumulative hypergeometric distribution analysis to determine if any statistically significant gene ontology co-clustering has occurred.
Added: Sat Apr 03 2010, Hits: 1955, Reviews: 0
(Institute of Computer Science, University of Tartu)
g:GOSt retrieves most significant Gene Ontology (GO) terms, KEGG and REACTOME pathways, and TRANSFAC motifs to a user-specified group of genes, proteins or microarray probes. g:GOSt also allows analysis of ranked or ordered lists of genes, visual browsing of GO graph structure, interactive visualisation of retrieved results, and many other features. Multiple testing corrections are applied to extract only statistically important results.
Added: Sat Apr 03 2010, Hits: 2549, Reviews: 0
Gene Functional Classification
(Laboratory of Immunopathogenesis and Bioinformatics, NIAID)
The Functional Classification Tool provides a rapid means to organize large lists of genes into functionally related groups to help unravel the biological content captured by high throughput technologies.
Added: Sat Apr 03 2010, Hits: 2315, Reviews: 0
(Institute of Genetics and Developmental Biology, Chinese Academy of Sciences)
GOEAST is web based software toolkit providing easy to use, visualizable, comprehensive and unbiased Gene Ontology (GO) analysis for high-throughput experimental results, especially for results from microarray hybridization experiments. The main function of GOEAST is to identify significantly enriched GO terms among give lists of genes using accurate statistical methods.
Added: Sat Apr 03 2010, Hits: 1521, Reviews: 0
(Technion - Laboratory of Computational Biology)
GOrilla is a tool for identifying and visualizing enriched GO terms in ranked lists of genes.
It can be run in one of two modes: 1. Searching for enriched GO terms that appear densely at the top of a ranked list of genes or 2. Searching for enriched GO terms in a target list of genes compared to a background list of genes.
Added: Sat Apr 03 2010, Hits: 1374, Reviews: 0
(Walter and Eliza Hall Institute of Medical Research)
Find statistically overrepresented GO terms within a group of genes
Added: Sat Apr 03 2010, Hits: 1753, Reviews: 0