How to prevent membrane bound receptor from endocytosis - (May/31/2005 )
Hi,
I have a question about receptor endocytosis. How can I prevent the receptor from endocytosis upon ligand binding? Is there any chemical I can use? Thanks a lot.
Jun
-Shenjun-
I believe sodium azide is an effective inhibitor of ligand mediated internalization. Also putting your cells on ice should do the trick.
-MaximinaNYC-
QUOTE (Shenjun @ May 31 2005, 10:18 AM)
Hi,
I have a question about receptor endocytosis. How can I prevent the receptor from endocytosis upon ligand binding? Is there any chemical I can use? Thanks a lot.
Jun
I have a question about receptor endocytosis. How can I prevent the receptor from endocytosis upon ligand binding? Is there any chemical I can use? Thanks a lot.
Jun
Hi,
Thank you very much for your help.
Jun
-Shenjun-