Pioneers of Mutagenesis to Probe Protein Structure and Function - (Dec/06/2008 )
I'm giving a lecture called "The Biochemists' Toolbox." My lecture will consist of the aspects of protein engineering (expression vectors, expression systems, and probing protein structure/function via mutagenesis). I'm having trouble finding the pioneers of this field. I'm well aware of PCR (Kary Mullis), however, I don't know where to look for the rest. Any suggestions? Any classical experiments in this field anyone's aware of?
You just might find something interesting in these Protein Structure & Function lectures.