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miRNA family - (Aug/22/2008 )

Dear all,

Hi, can anyone tell me what is the criteria to determine the family of a microRNA? Can u plz suggest me journals or other references that have clear explanation on this.

And, do microRNA precursor (pre-miRNA) have polyA tail like that primary microRNA (pri-miRNA)

Thanx..

-Yew-

Gooogle the defination for microRNA family
Pre-miRNAs have been processed to around 70 bp hairpin 2nd structure product, I do not think they have polyA tail.




-microlight-

QUOTE (Yew @ Aug 22 2008, 09:38 AM)
Dear all,

Hi, can anyone tell me what is the criteria to determine the family of a microRNA? Can u plz suggest me journals or other references that have clear explanation on this.

And, do microRNA precursor (pre-miRNA) have polyA tail like that primary microRNA (pri-miRNA)

Thanx..

For nomenclature, check out this paper: PMID: 16381832

The pre-miR has no polyA tail.

-miRNA man-