Can RNAi be used for silencing of non-coding RNAs? - (May/26/2008 )
I was just curious to know
'm curious too.
Since the siRNA target any rna, you could knockdown non-coding RNAs.
Yes, it is possible. Check this paper Specific and potent RNAi in the nucleus of human cells
Great! Thanks. I'm doing this theoretical laboratory project where I have to target human telomerase as a cancer therapy. TERC, prepare for silencing
Theoretical? You will be a great PI