polyclonal vs monoclonal - (May/17/2008 )
Hi everyone...just trying to wrap my head around antibody stuff...
polyclonal antibodies are primarily igg - produced from B cells, correct?
what are monoclonal considered to be as far as class...igg, igm, igy? thanks!
both poly n monoclonal antibodies are igGs n produced from B cells,
polyclonal has more than one subclasses
monoclonal has sigle subclass, as it is derived from single clone.
u donot find any other types except igM, but the presence igM depends on immunization schedule.
Monoclonals are produced from a hybridoma - a fusion of a b-cell taken from an animal that has been challenged by an antigen, and a myeloma cancer cell. They are essentially immortal and only produce one type of antibody.