question about dendritic cells and antigen-specific T cells - (Mar/22/2007 )
I wonder whether some of my comprehension on DC and antigen-specific T cells is true.
Papers say after DCs capture antigens they will move into lymph organs in search of antigen-specific T cells.
And they say T-cell clones aiming at a certain antigen are very rare: usually at a frequency of 1/100,000 or less.
So I'm thinking the following thing.
Assuming a DC presenting antigen A was placed with 100,000 T cells in vitro, coincidently there is no antigen A-specific
T cell in this group of T cells. So these T cells won't kill any target cells expressing antigen A.
Am I right?
Hope for response