Protein Full Names - (Jun/01/2006 )

What does the abbreviation of Akt, Src, Syk mean.

Google says Src, Syk and Akt are all families of protein kinases.

Akt (Protein Kinase , other reference

Src is for sarcoma

protein tyrosine kinase (PTK) syk : i believe Y stads for tyrosine, and so syk is the motif recognized by this prote'in.

As the other said they are all proteins kinases.

Akt is also known as Protein kinase B (PKB) and is downstream of PI3 kinase.
See http://www.emdbiosciences.com/html/cbc/akt...e_substrate.htm

Syk is downstream of the B-cell receptor and Src is involved in several pathways (receptor tyrosine kinases, TCR etc.)

Sorry you asked what the abbreviations stood for:-

Spleen tyrosine kinase (Syk)

Not sure about Akt. Sometimes as protein kinases are oncogenes it's taken from the cancer they were first identified it. I think it stands for AKT8-induced thymoma possibly because it was isolated from an oncogenic retrovirus which caused thymomas?

Proc Natl Acad Sci U S A. 1987 Jul;84(14):5034-7. Related Articles, Links
  
Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma.
Staal SP.
A previous report described the isolation of a directly transforming retrovirus, AKT8, from a spontaneous thymoma of an AKR mouse. The AKT8 provirus has now been molecularly cloned from a transformed, nonproducer cell line. The virus genome contains both viral and nonviral, cell-related sequences; the nonviral sequence has been designated v-akt, the presumed viral oncogene of the AKT8 virus. This gene lacks homology to the 16 other oncogenes tested. The cloned provirus has undergone a partial deletion, during cell passage in vitro, that prevents direct demonstration of the transforming ability of this molecular clone. Two human homologues of the v-akt oncogene, AKT1 and AKT2, were cloned. A survey of 225 human tumors for changes involving AKT1 led to the discovery of a 20-fold amplification of this gene in one of the five gastric adenocarcinomas tested. The results demonstrate that AKT8 has the characteristic structure of a directly transforming retrovirus and that it contains a gene derived from highly conserved cellular sequences that may be involved in the pathogenesis of some human malignancies.

All the best,
Ceri