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about Band - genomic DNA of liver of mouse (Apr/17/2006 )

After isolation of genomic DNA from liver of mouse by Tri-reagent, is it give single band or smear of genomic DNA.


a smear is not a good sign! you want one really big band!


you most probably have a large amount of contaminating RNA in the sample, try using RNAse during isolation

-grapes of wrath-