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Phenol chloroform extraction of DNA - (Apr/08/2009 )

I'm writing up a lab report and I was wondering if anybody had a link to a good explanation to the theory behind a phenol chloroform extraction of DNA?

Thanks

-Nilafhiosagam-

Not a link, but try finding a copy of Sambrook, Fritsch and Maniatis, Molecular Cloning: A Laboratory Manual.

-bob1-

Different solubilities. Nucleic acids are more soluble in water, and thus predominate in the aqueous phase, whereas proteins prefer an organic solvent, and thus separate to the phenolic phase.

-HomeBrew-

Thank you for the replies.

-Nilafhiosagam-