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DNA shearing with Misonix 4000 and microplates cup horn - (Mar/11/2009 )

Hi everybody,
I'm going crazy trying to shear the DNA of my Saos2 and MCF-7 with a Misonix 4000 sonicator with a microplate cup horn.
Any suggestion?


What is your propblem? unable to shear DNA? what conditions are you using. Without any of these info, it is hard to troubleshoot.


there is a girl also doing DNA shearing with sonication. maybe you can have a communication.

but I want to know how to see or download the attatchment in the following site: