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values for mRNA molecules per cell - (May/03/2012 )

Hi folks,

I am looking for reliable numbers of abundane of mRNA species in human cells (in molecules per cell or M), or at least a rough estimates like for a housekeeping gene / a typical transcription factor the numer is x / cell.

I guess the concentration also varies largely and depends on different factors like cell volume variation, cell cycle etc. Can you recommend papers on that?

Thanks a lot,


Roche Lab FAQs suggest that the total RNA per cell is about 100 fg and the proportion of mRNA is 1-5%.