BioProduct : Chemicals & Compounds : Gefitinib
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Product Name Gefitinib
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Product Description MCF10A cells are nontransformed breast epithelial cells that require EGF to proliferate.The monolayer growth of these EGF-driven untransformed cells is inhibited by ZD1839 with an IC50 of 20 nM, similar to its IC50 in vitro for EGFR and consistent with effective inhibition of EGFR in vivo. Cell line characteristics and sensitivity to ZD1839 at 1uM are 59% inhibition for MDA-MB-231,74% inhibition for A431, 81% inhibition for SKBr3,60% inhibition for SKOV3, 33% inhibition for BT474,52% inhibition for MCF-7, 28% inhibition for T47D, respectively.
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Price $85
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Vendor Information Selleck
2626 South Loop West, Suite 225, Houston, TX 77054 USA