lysosomes in cells - (Sep/20/2005 )
well im doing a power point on lysosomes and i cant find anything on what types of cells there in. any idea what type of cells there in? thanks
Eukaryotic cells? Human & Ms fibroblasts, Monkey kidney cells, etc.
FOUND THIS DOING A GOOGLE SEARCH FOR 'LYSOSOME'
THERE WERE MANY OTHER PAGES AS WELL
Discovered in 1950 by Rene de Duve, a lysosome is a tiny organelle found in all eucaryotic cells. The lysosomes are more or less the wrecking crew of a cell. They digest macromolecules such as monosaccharides and break down damaged or old cell parts as well as bacteria.
Each lysosome is surrounded by its own membrane due to the acidic conditions within it. They contain hydrolytic enzymes that break down whatever is necessary. These enzymes are only active within the acidic membrane of the lysosome so that in case of leakage or rupture, the enzymes will not be active within the cell.
Lysosomes are formed off of the membrane of the trans-golgi. Materials to be digested reach the enzymes through endocytosis, where a macromolecule is taken into the cell y an endosome. The lysosome then fuses with the membrane of the endosome and begins to break down the macromolecule. Autophagocytosis. In this process, an old or damages organelle are enveloped by endosomes and then fused to lysosomes. Phagocytosis is the process where extra cellular particles such as bacteria, are engulfed in the cell and then fused to lysosomes for digestion.
It is clear just how important the lysosome is due to the diseases that are caused when there is a defect in the structure of the hydrolytic acid. If the acid cannot digest and break down the necessary particles or organelles, there can be an extreme build up of these in the cell. Hurler's Syndrome which is a direct result of this deficiency can result in severe physical deformity and damage.