signaling cascade - cell bio (May/08/2005 )
Hey everyone, I was doing some work in cell bio and I got stuck on this problem. Can anyone figure it out and explain it please? Thanks in advance!
In muscle cells, epinephrine binds to the Beta-adrenergic receptor to initiate a signaling cascade that leads to the breakdown of glycogen. At which points in this pathway is the signal amplified?
chart
A critical feature of all signaling cascades is that they must be turned off rapidly when the extracellular signal is removed. Examine the signaling cascade in the chart (the link) and describe how each component of the pathway is returned to its inactive state when epinephrine is removed.
One again I suggest you look these answers up on your own in textbooks, us giving them to you isn't going to help you learn anything. The answer to both parts of your question are word for word in Lodish's Molecular Cell Biology (among others).
In muscle cells, epinephrine binds to the Beta-adrenergic receptor to initiate a signaling cascade that leads to the breakdown of glycogen. At which points in this pathway is the signal amplified?
chart
A critical feature of all signaling cascades is that they must be turned off rapidly when the extracellular signal is removed. Examine the signaling cascade in the chart (the link) and describe how each component of the pathway is returned to its inactive state when epinephrine is removed.