differences in posttranslational modification - (Jan/09/2005 )
Does anybody know the differences in post-translational modification between yeasts, bacteria and mammalian cells?
Thanks
-lijia-
Hello,
I'm not a 100% sure but from my understanding there are no post-translational modifications in bacteria well lets say not as many as in yeast and mammalian cells. Bacteria cell will not perform glycosylation and phosphorylations at least. Yeast and mammalian cells will overall do the same postranslational modifications but there might be some slight differences, even from species to species. For instance, the type of sugar and the lengh of it will probably be different in a glycosylation.
Hope this helps you,
-tweete07-
QUOTE (tweete07 @ Jan 15 2005, 11:02 AM)
Hello,
I'm not a 100% sure but from my understanding there are no post-translational modifications in bacteria well lets say not as many as in yeast and mammalian cells. Bacteria cell will not perform glycosylation and phosphorylations at least. Yeast and mammalian cells will overall do the same postranslational modifications but there might be some slight differences, even from species to species. For instance, the type of sugar and the lengh of it will probably be different in a glycosylation.
Hope this helps you,
I'm not a 100% sure but from my understanding there are no post-translational modifications in bacteria well lets say not as many as in yeast and mammalian cells. Bacteria cell will not perform glycosylation and phosphorylations at least. Yeast and mammalian cells will overall do the same postranslational modifications but there might be some slight differences, even from species to species. For instance, the type of sugar and the lengh of it will probably be different in a glycosylation.
Hope this helps you,
Meep. Sorry, but bacteria do have a large amount of post-translational modifications. Take phosphorylation for example.. Bacteria have a lot of two component regulation systems, which of course effect phosphorylation status via the cognate kinases.
And although there are far less examples for bacterial glycosylation, they do exist. Several surface proteins (e.g. S-layers) are known to be glycosylated, however the composition of the sugars are usually very divergent from eukaryotes.
-Charon-