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p53 in yeast? - (Nov/19/2008 )

Hello everyone,
I hope that's the right forum for this question, anyway here I go:
is there any homologue of human TP53 gene in yeast or it is something less primitive into evolution?
I could only find works on human p53 activity in yeast, but nothing about any endogenous homologue... huh.gif
Does anyone know?

-doglo-

QUOTE (doglo @ Nov 19 2008, 10:08 AM)
Hello everyone,
I hope that's the right forum for this question, anyway here I go:
is there any homologue of human TP53 gene in yeast or it is something less primitive into evolution?
I could only find works on human p53 activity in yeast, but nothing about any endogenous homologue... huh.gif
Does anyone know?

I don't think there is endogenous yeast homolog of p53 despite the fact that it works. Anyone else know better..?

-cellcounter-

QUOTE (cellcounter @ Nov 20 2008, 05:15 AM)
QUOTE (doglo @ Nov 19 2008, 10:08 AM)
Hello everyone,
I hope that's the right forum for this question, anyway here I go:
is there any homologue of human TP53 gene in yeast or it is something less primitive into evolution?
I could only find works on human p53 activity in yeast, but nothing about any endogenous homologue... huh.gif
Does anyone know?

I don't think there is endogenous yeast homolog of p53 despite the fact that it works. Anyone else know better..?

Actually I have found a review that state that no homologue of p53 has been found in yeast, but it was written in the fabulous '90 (Soussi T, May P. Structural aspects of the p53 protein in relation to gene evolution: a second look. J Mol Biol. 1996 Aug 2;260(5):623-37. Review.)!

-doglo-