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Any drug that can cause male mice infertile? - (Jan/29/2008 )

Hello everyone,
Is there any drug that can cause male mice infertile?
And the corresponding drug resistance gene?

Thank you.

-WHR-

QUOTE (WHR @ Jan 29 2008, 11:09 PM)
Hello everyone,
Is there any drug that can cause male mice infertile?
And the corresponding drug resistance gene?

Thank you.


do you mean reversible or irreversible?

in the case of reversibility, I would try testosteron (testosteronundecanoate, or synthetic such as MENT); giving gestagens enhances the effect; it should result in azoospermy

-The Bearer-

QUOTE (The Bearer @ Feb 3 2008, 03:12 AM)
QUOTE (WHR @ Jan 29 2008, 11:09 PM)
Hello everyone,
Is there any drug that can cause male mice infertile?
And the corresponding drug resistance gene?

Thank you.


do you mean reversible or irreversible?

in the case of reversibility, I would try testosteron (testosteronundecanoate, or synthetic such as MENT); giving gestagens enhances the effect; it should result in azoospermy


Thank you The Bearer,
I hope to inactivate endogenous spermatogenesis(either reversible or irreversible) and only the modified SSC can function normally.

-WHR-