Poly-Lysine and Pastic coating - (Jun/22/2007 )
Does anyone knows the difference between Poly-L-Lysine and Poly-D-Lysine treatment on plastic for cell's adherence???
Thanks a lot
poly-D-lysine and poly-L-lysine are both usable to cover. They are equivalent.
But poly-D-lysine is often favored because the D-enantiomer is less prone to protease-mediated breakdown (L-enantiomers are usually the naturally occuring ones...).
We use poly-D-lysine for coating glass coverslips. I dont know the difference in treatment between D and L enantiomers.
Thanks a lot for your knowledge. I will try next time with poly-D-lysine.
Have a nice day