Frequency of flanking alleles? - (Nov/21/2006 )
I'm working on a model (haploid), with one round of recombination, to see how allele frequencies change over time on either side of a selected allele.
In a text book I found that, given a selected allele, the frequency of flanking alleles is 1-r, where r is the recombination fraction.
Can anyone explain why this is so?? For example, if the frequency of a selected allele is, say 0.4, how do I work out the frequency of the flanking alleles from the above statement??
I know what the recombination fraction is, from a Haldane map function, but I just don't know how to fit everything into the above equation to work out the frequency of the flanking alleles.
Any help would be great!
188.8.131.52 Genetic interference in the link below should help to explain it.
Excellent, that helped a lot, thanks!