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murine breast tumor model ? - murine breast tumor model ? (Jun/29/2006 )

hello all,

i am new in animal cell culture

i need murine breast tumor model to study, immunogenicity of anti tumor formulations
Is it O.K. , If i use C 1271 mammary tumor cell to induce tumor in BALB/c mice.

can i measure dimensions of the so induced tumor, in above CASE ( IT would be
helpful to me , as i can use tumor size as ,one of the parameter to access
vaccine efficacy).

similarly also suggest few tumor cell for BALB/c mice , which when injected

induce solid tumor in BALB/c mice.
vms huh.gif

-vmsy2k-

QUOTE (vmsy2k @ Jun 29 2006, 06:39 AM)
hello all,

i am new in animal cell culture

i need murine breast tumor model to study, immunogenicity of anti tumor formulations
Is it O.K. , If i use C 1271 mammary tumor cell to induce tumor in BALB/c mice.

can i measure dimensions of the so induced tumor, in above CASE ( IT would be
helpful to me , as i can use tumor size as ,one of the parameter to access
vaccine efficacy).

similarly also suggest few tumor cell for BALB/c mice , which when injected

induce solid tumor in BALB/c mice.
vms huh.gif


Sorry, I do not know what is C1271 mammary tumour cell.
Yes you can measure the size of the induced tumour for determine the vaccine efficacy.
66c14 mammary tumour cell line can be use in BALB/c mice

I hope this may help

-Minnie Mouse-