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Ferulic Acid - 'sequence type', 'against type'? - (May/26/2006 )

Hi,

I use standardized botanical extracts in my home made skin care products.

One extract that is the current 'flavor of the month' is Ferulic Acid. This is mainly based on one study (Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin.
Lin FH, Lin JY, Gupta RD, Tournas JA, Burch JA, Selim MA, Monteiro-Riviere NA, Grichnik JM, Zielinski J, Pinnell SR. Duke University Medical Center, Durham, North Carolina 27710, USA.
)

I recently received this info from a retailer:

QUOTE
Natural ferulic acid is similar white to white power. It is divided into 'sequence type' and 'against type'. 'Sequence type' is yellow and 'against type' is white. A synthetic Ferulic acid is also available


I did a lot of searching to get more information on these two types, and their differences. But was unable to find much.

Would any one be able to direct me to the right place where the different 'types' of Ferulic Acid are exlained in a simplified way (for a non-scientist).

I am also confused about the 'synthetic' ferulic acid. I thought that Ferulic Acd was used to create a synthetic form of vanilla. I did not realise that it was also possible to create synthetic Ferulic.

Thank you for any help!

-skincare-

QUOTE (skincare @ May 26 2006, 07:36 PM)
Hi,

I use standardized botanical extracts in my home made skin care products.

One extract that is the current 'flavor of the month' is Ferulic Acid. This is mainly based on one study (Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin.
Lin FH, Lin JY, Gupta RD, Tournas JA, Burch JA, Selim MA, Monteiro-Riviere NA, Grichnik JM, Zielinski J, Pinnell SR. Duke University Medical Center, Durham, North Carolina 27710, USA.
)

I recently received this info from a retailer:

QUOTE

Natural ferulic acid is similar white to white power. It is divided into 'sequence type' and 'against type'. 'Sequence type' is yellow and 'against type' is white. A synthetic Ferulic acid is also available


I did a lot of searching to get more information on these two types, and their differences. But was unable to find much.

Would any one be able to direct me to the right place where the different 'types' of Ferulic Acid are exlained in a simplified way (for a non-scientist).

I am also confused about the 'synthetic' ferulic acid. I thought that Ferulic Acd was used to create a synthetic form of vanilla. I did not realise that it was also possible to create synthetic Ferulic.

Thank you for any help!


Firstly, ferulic acid is a single chemical, not an extract (which implies to me some sort of mixture). I suspect they haven't the foggiest idea what they're talking about when referring to sequence type and against type, you don't say what type of retailer this is, but I'll assume it's not a normal scientific chemical supplies company, as they would never talk about a simple chemical in such a way.

They could be talking about the two chemical forms 'cis' and 'trans', which is to do with the positioning of the double bond in the ferulic acid (no difference to it's normal chemical properties as far as I know, but may be some difference if ingested). I'm not sure why the colour would be different though. Ferulic acid is quite a simple chemical so it can be synthesised in a chemical plant as well as being found in a huge array of plants (hence chemical doesn't necessarily mean bad). I think if it was me I would want to ask the retailer exactly what they mean by sequence type and against type. Also most chemicals should come with a Material Safety Data Sheet (MSDS), which should tell you whether there would be any problems with bad reactions.

Hope this helps a bit.

The wikipedia entry, while not perfect, gives some information on ferulic acid.
http://en.wikipedia.org/wiki/Ferulic_acid

-Grast-