Eukaryote's RNA Polimerases - transcription 3' to 5'? (Apr/20/2006 )
I got a question on a test, it said: Why eukaryotic RNA polimerase, contrary to prokaryotic RNA polimerase, transcribe 3' to 5'?
As far as I know all RNA polimerases transcribe 5' to 3', so I answered that but I got it wrong. I have been looking but I find no answer, Can somebody help me with this issue? I would appreciate it to much. I'm mad about that bad note =(.
RNA polymerases are DNA dependent enzymes that are capable of elongationfrom 3' OH terminus. So they are 5'3' RNA DNA-dependant polymerases.
I think the pb is elsewhere...
The polymerases read the template strand in sense 3' to 5' in order to elong 5' to 3' complementary.