What are the morphologic features of cells undergoing dedifferentiation - (Feb/24/2006 )

Hello All,

Could someone tell me what are the typical morphological features when a cell is undergoing dedifferentiation? I am studying epithelial cells and do notice some morphological changes after treatment but don't know if they are characteristic of dedifferentiation.

Thank you in advance.

K

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Hi,
What is the source of your epithelial cell? The morphology cannot certify that a cell is undergoing de-differentiation. You have to show something biochemically (immunostaining, PCR ,western) to show that the cell shuttles between two differentiated adult kind to prove dedifferentiation.
Best,
A

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if you find and prove the dedifferentiation of special cells, you may deserve a big paper!!

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