Recognizing whether the cells are cancerous. - (Nov/22/2005 )
Hi, I will really appreciate if someone could help:
I have two stable lines cell populations: the control and protein x(-) cells (they express only 5%
of x). X(-) cells behaves in a very strange way: they have prolong signaling, receptors that have to go to degradation, in x(-) cells go to recycling and they look different.
Are there some methods to check whether this cells have a cancerogenous potential?
Before I go to the nude mice.
Thanks.
Sem
-sem-
QUOTE (sem @ Nov 22 2005, 01:14 PM)
Hi, I will really appreciate if someone could help:
I have two stable lines cell populations: the control and protein x(-) cells (they express only 5%
of x). X(-) cells behaves in a very strange way: they have prolong signaling, receptors that have to go to degradation, in x(-) cells go to recycling and they look different.
Are there some methods to check whether this cells have a cancerogenous potential?
Before I go to the nude mice.
Thanks.
Sem
I have two stable lines cell populations: the control and protein x(-) cells (they express only 5%
of x). X(-) cells behaves in a very strange way: they have prolong signaling, receptors that have to go to degradation, in x(-) cells go to recycling and they look different.
Are there some methods to check whether this cells have a cancerogenous potential?
Before I go to the nude mice.
Thanks.
Sem
Well in the past when I was working on overexpression of c-jun members we use the Agar growth if the cells can replicate on soft Agar they have a potential of immortalize cells !
here you will find a previous topicon this subjectSoft agar and so on...
-pesji-