MOCK INFECTED CELLS - (Feb/11/2009 )
can anyone explain what Mock infected cells mean and give me some examples about materials to mock infection?
It's when you infect cells with an empty vector. It's the control.
little mouse on Feb 11 2009, 04:51 AM said:
thanks yes it is for control but can you explain more. I'm new in this field.
I guess that the infected cells are infected with a viral vector, to express a protein of interest, or to knockdown the expression of a protein. From this expression or knockdown of expression, you oberve a response. To be sure that the response is due to the expression of a protein, and not due to the infection itself, you infect control cells with the same viral vector but empty. It means it won't express the protein of interest.
I asked the same question last week: