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How clean do I need my DNA to be? - (May/18/2017 )

I have been using kits with columns to purify genomic DNA which I then use as a template for PCR for sequencing or T7E1/CelI mutation-detection assays. I accidentally ordered a kit which does not use columns but rather the older approach of chloroform and ethanol precipitation. I think it should be fine but then I wonder why I've been using spin columns... just for convenience? 

-seanspotatobusiness-

Partly correct, convenience is one of the features; they also save time, which, if you are employed, is frequently the biggest cost for any experimental laboratory.

-bob1-