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Converting clinically relevant dose for in vitro studies - (Jan/30/2015 )

Hi, can anyone suggest how to convert clinically relevant doses for in vitro studies. For example, say the clinically relevant dose for 5FU is 400 mg/m2; how do I convert it for MTT drug response assays. Tq


Bump. I am also interested in finding out how they do it. I mean actually, not guesswork.