What is the RNA:Protein ratio for ONE gene over different RNA levels? - (May/21/2014 )
I've spent a long time trying to find the basic answer to this question:
What is the RNA:Protein ratio for ONE gene over different RNA levels? Lets say in E. coli for simplicity's sake.
In other words, if an inducible gene, such as lacZ expresses different amounts of mRNA depending on the level on induction, how would the B-galactosidase protein concentration change with varying RNA concentration? Would the relationship be linear, quadratic, log?
I'm looking for experimental evidence. Thanks!!
I don't know the answer for sure, but I suspect that it will depend on the gene! For many the relationship will be 1:1, but there may well be cases where the mRNA is used multiple times.