miRNA knockdown in a mouse, tail vein injection (~50% KD) - (Nov/08/2013 )
Sun Y, Li Q, Gui H, Xu DP, Yang YL, Su DF, Liu X. MicroRNA-124 mediates the cholinergic anti-inflammatory action through inhibiting the production of pro-inflammatory cytokines. Cell Res. 2013 Nov;23(11):1270-83. doi: 10.1038/cr.2013.116. Epub 2013 Aug 27.
Supplementary figure S3 shows the knockdown after systemic (tail-vein) treatment.
Did you have a question?
Not at the moment, thanks. Just a nice citation to an in-vivo miRNA manipulation by a Shanghai/NCI collaboration.