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Tamoxifen citrate solubility for cell work?? - (Jan/09/2013 )


I've been trying to dissolve Tamoxifen in 2%DMSO to be used for cell culture work. However, it seems to be insoluble in 2%DMSO. It only dissolves in 50% ethanol. This however, is not suitable to be used for cell culture works.

I have to do a cytotoxicity study of tamoxifen on MDAMB 231 cell lines.

Has anyone encountered this problem previously. can't seem to find a solution to this.

Thanks in advance.


At what concentration? What is the DMSO diluted with?