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siRNA in E.Coli - (Jan/04/2013 )

Do E.coli have siRNA Metabolism?


Nope. But bacteria have a similar mechanism called CRISPRs (C lustered R egularly I nterspaced S hort P alindromic R epeats).which confers resistance to exogenous genetic elements such as plasmids and phages. This mechanism also uses RNA as guide, but use proteins other than AGO as in eukyaroytes.


Sounds good.Thanks.