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What are alternatives to Xenopus eggs? - (Nov/19/2012 )

I am reading this article about nuclear membrane and pores. They use the cellular content of Xenopus frog eggs to study chromatin binding.

my question is, why don't they just use culture cells instead of growing frog eggs? I mean, it is difficult to take care of frogs and breed them to produce eggs. After all their concern is eukaryotic nucleporins. just why not use cells in the flask?


Eggs = big, and literally covered with membrane transporters, cultured cells = small and generally not so densly covered with transporters.

It actually isn't difficult to care for and produce eggs from Xenopus, and you can get a LOT of eggs from one frog.


thanks bob1, as always.