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What's so challenging about metablomics? - (Jun/10/2012 )

What makes metablomics more complicated than proteomics?
Why are there so very few people/labs that are good at it? Do the complexities arise from the nature of the cell itself
or researchers just waiting for high-thoroughput technology to come along and make life easier?

Just curious because I'm studying proteomics right now, and my lecturer has included a rather short section on metablomics
... but I'm given to understand that metabolites actually provide the best 'snapshot' of what is going on inside a cell.

edit: ALSO... when extracting samples fro tissues, how do you make sure you're not getting any components of the 'proteome' in there?
Is it something along the lines of using molecular sieves to retain the smallest compounds?


Firstly the name?