Alternatives to benzonase? - (Feb/24/2012 )
I'm currently undertaking a purification protocol that requires the use of fairly large amounts of benzonase as my protein is quite contaminated with nucleic acid. As benzonase is not the cheapest reagent I was wondering if anyone was aware of any generic alternative nucleases that might proivde a cheaper alternative.
Thanks for your help.
A member of our lab simply treats her purified protin with DNAse to remove DNA.. Works fine for her and is pretty cheap