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What does metaplasticity mean? - (May/17/2011 )

I know the term "synaptic plasticity" but what does "synaptic metaplasticity" mean? oO Any idea?

-Inmost sun-

I believe it refers to changes in the ability of neurons to undergo the changes in their firing properties typical of synaptic plasticity. It's basically "plasticity of synaptic plasticity"


 metaplasticity entails a change in the physiological or biochemical state of neurons or synapses that alters their ability to generate synaptic plasticity.


Actually, you should check out this great lecture on presynaptic plasticity:


thank you, that´s helpful

-Inmost sun-