miRNA LNA - how can I designed a scramble ? (Apr/12/2011 )
Before testing my antimir LNA, I've to design a scramble LNA ( for the control ). How can I know wich sequence to use for the scramble control ? Is it a pure random sequence ? a permutation of my miRNA to inhibit ?
Both are OK as long as the control sequence does not have significant homology with any miRNA sequence.