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My DNA pellet doesn't dissolve - Overdried?? (Feb/22/2011 )


I did a DNA extraction but now I can't dissolve the pellet in TE. I think I might have overdried the pellet. What can I do? The tubes are currently at 37 C, but no luck until now.

Thanks in advance.


keep it at 37C and give it some time


Dissolve the DNA overnight on a shaker or at 55C for 12 h.
this was what i did using Qiagen genomic DNA extraction kit.


Thanks, I will try that right now!