Number of proteins expressed in cell - (Apr/29/2010 )
Does anyone know how many different proteins are expressed in a mammalian cell?
I know there is supposed to be between 10 - 20 thousand but can anyone give me a reference for this?
Has there been a proteomic study done to answer this question?
I guess that you can look at the genome and use the number of genes found as an estimate of the number of proteins expressed. However, not all cells will express all genes and there are things like expressed pseudogenes that complicate things a bit.
From Background Information on the Human Proteome and the Yale/NHLBI Proteomics Center.
The fact is, we just don't know how many proteins comprise the human proteome -- a project to find out was started last year (see here).