Chromosomes in metaphase - (Nov/05/2009 )
What happens to DNA methylation when cells are in metaphase?
The reason I'm asking this is because I want to find out whether we can use FACS to isolate chromosomes and for next generation sequencing without having to sequence the whole genome...
that is a good question and I don't think anyone knows.
one would assume by metaphase the copying of epigenetic information post S-phase is complete, so nothing happens to it at metaphase.