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Latest Scientific Breakthroughs

Articles in Press from Science, Nature, Cell and the Lancet. Updated daily
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Nature Genetics - Advance Online Publication (AOP)
• An atlas of alternative polyadenylation quantitative trait loci contributing to complex trait and disease heritability (Nature Genetics, 2021-05-13)
• The SWI/SNF chromatin remodeling complex helps resolve R-loop-mediated transcription–replication conflicts (Nature Genetics, 2021-05-13)
• Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands (Nature Genetics, 2021-05-13)
• Histone acetylation dynamics modulates chromatin conformation and allele-specific interactions at oncogenic loci (Nature Genetics, 2021-05-10)
• Ultrafast Sample placement on Existing tRees (UShER) enables real-time phylogenetics for the SARS-CoV-2 pandemic (Nature Genetics, 2021-05-10)
• Long-read sequencing of 3,622 Icelanders provides insight into the role of structural variants in human diseases and other traits (Nature Genetics, 2021-05-10)
• Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence (Nature Genetics, 2021-05-10)
• Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson’s disease (Nature Genetics, 2021-05-06)
Science - Sciencexpress
• Socioeconomic status determines COVID-19 incidence and related mortality in Santiago, Chile (Science, )
• Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome (Science, )
• Very weak bonds to artificial atoms formed by quantum corrals (Science, )
• Role of the ionic environment in enhancing the activity of reacting molecules in zeolite pores (Science, )
• Quantum walks on a programmable two-dimensional 62-qubit superconducting processor (Science, )
• Structures of the human Mediator and Mediator-bound preinitiation complex (Science, )
• Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes (Science, )
• Resurgence of SARS-CoV-2: detection by community viral surveillance (Science, )
• Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose (Science, )
• Dynamic remodeling of host membranes by self-organizing bacterial effectors (Science, )
• Household COVID-19 risk and in-person schooling (Science, )