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#149536 Test for heparan sulfate functionality?

Posted by C8H10N4O2 on 04 February 2013 - 05:48 AM in Protein and Proteomics

I'm wondering if there is an assay that can test for heparan sulfate binding function. I'm not that familiar with protein interactions studies, I primarily work with virology and cell biology.
I have tested heparan sulfate and it's effect on our virus ability to bind to cells, and we have found that it has no effect. What I now need is a way to show that the heparan sulfate is actually working in binding other proteins so that the lack of effect is due to our virus inability to bind to it.

Is there someone out there that has any advice on how I should do this?


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