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Latest Scientific Breakthroughs

Articles in Press from Science, Nature, Cell and the Lancet. Updated daily
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Nature Genetics - Advance Online Publication (AOP)
• Publisher Correction: BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange–like syndrome (Nature Genetics, 2018-02-12)
• Stress and sexual reproduction affect the dynamics of the wheat pathogen effector AvrStb6 and strobilurin resistance (Nature Genetics, 2018-02-12)
• Wheat receptor-kinase-like protein Stb6 controls gene-for-gene resistance to fungal pathogen Zymoseptoria tritici (Nature Genetics, 2018-02-12)
• CLCN2 chloride channel mutations in familial hyperaldosteronism type II (Nature Genetics, 2018-02-05)
• A gain-of-function mutation in the CLCN2 chloride channel gene causes primary aldosteronism (Nature Genetics, 2018-02-05)
• Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases (Nature Genetics, 2018-02-05)
• Exome-wide analyses identify low-frequency variant in CYP26B1 and additional coding variants associated with esophageal squamous cell carcinoma (Nature Genetics, 2018-01-29)
• BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange–like syndrome (Nature Genetics, 2018-01-29)
Science - Sciencexpress
• Modular radical cross-coupling with sulfones enables access to sp3-rich (fluoro)alkylated scaffolds (Science, )
• CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity (Science, )
• Predicting reaction performance in C-N cross-coupling using machine learning (Science, )
• Detection and localization of surgically resectable cancers with a multi-analyte blood test (Science, )
• Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6 (Science, )
• Rewritable multi-event analog recording in bacterial and mammalian cells (Science, )
• Winter color polymorphisms identify global hot spots for evolutionary rescue from climate change (Science, )
• Phosphoric acid as a precursor to chemicals traditionally synthesized from white phosphorus (Science, )
• Rev-erb{alpha} dynamically modulates chromatin looping to control circadian gene transcription (Science, )
• Hippocampal ripples down-regulate synapses (Science, )
• Diurnal transcriptome atlas of a primate across major neural and peripheral tissues (Science, )