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The DNA encoding the Ig heavy chain isolated from a B lymphocyte synthesising an IgG2 antibody specific form diptheria toxin has the overall sequence:-
5'-V17D5J2Cgamma2-Cgamma4-Cepsilon-3'
How many DNA deletions have taken place during the development of the B cell to obtain this sequence?My lecturer explained that there are 3 deltions occuring, I didnt quiet understand why. Would someone mind explaining it to me?
