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Lord Apoptosis

Member Since 14 Jan 2013
Offline Last Active Jan 21 2013 03:31 AM
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Topics I've Started

Human or Mouse TFG-beta1?

14 January 2013 - 08:35 AM

Hello everyone,

I'm going to start to work in chondrogenic differentiation of a mouse bone marrow MSCs immortalized cell line. We still have a lot of human TFG-beta1 from other works. My doubt is about using this human factor in mouse cells. I have seen in blastp that the translated sequence for the mouse mRNA have a big match with the human one, but  it also has with human TGF-beta3. Any advice, please? If i could use the growth factor it woul be great, because it's an expensive material.

Thanks.

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