In addition 2 complement inactivation, heat inactivation was believed 2 inactivate adventitious microbial contaminants such as mycoplasmas...
U can find drawbacks of heat inactivation here:
heat inactivation increases the formation of precipitates (which are frequently mistaken for a microbial contaminant) & decreases d growth promotion capacity of d serum
TY
https://fscimage.fis...nactivation.pdf





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