In antibiotic broad spectrum (A broad-spectrum antibiotic acts against both Gram-positive and Gram-negative bacteria) and narrow spectrum antibiotics are groups. Amoxicillin comes under broad spectrum antibiotics so it can cure wide range of infections by acting against many bacteria. amoxicillin resistance is due to beta lactamase production in bacteria. clavulanic acid is suicide inhibitor for beta-lactamase. Hence amoxicillin /clavulanic acid combination is used.
Now to your actual question- what combination you are intending to use? is antibiotic u r using is broad spectrum or not? what inhibitor u r using? Is there study showing interaction between antibiotic and inhibitor? are they compatible(additive, synergistic) or antagonistic?
Agreed. Important question to consider.